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Greater activity promotes deeper, more restorative sleep
No dose above 2.4 mg has been carried forward
In the last years, a link between gut microbiota composition and autoimmune diseases has been proven in murine models and hypothesized in humans owed to the interactions with both the innate and adaptive branches of immunity [179]
In particular, increased plasma insulin concentrations stimulate the gonadotropin releasing hormone (GnRH) pulsatility and potentiate the LH-dependent effect on the ovarian theca cells, leading to the enhanced synthesis of androgens and to the arrest of pre-antral follicle development [13]
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