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During the randomized treatment period, patients received a standard lifestyle instruction every 12 weeks on reduced-calorie diet (approximately 500 kcal/day deficit) and increased physical activity (recommended minimum of 150 min/week) that began with the first dose of ZEPBOUND or placebo and continued throughout the 72-week treatment period
Microglia polarization from M1 to M2 in neurodegenerative diseases
Meanwhile, knowing the mechanism of GSH-responsive and -exhausting cancer treatment strategies based on metal nanomedicines is vital for selecting an optimized approach to GSH consumption and improving the efficiency of cancer therapy
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