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Lipoatrophy and severe metabolic disturbance in mice with fat-specific deletion of PPAR
They are not even playing on the same biological field
The only published human data are from 12 patients with interstitial cystitis (2024) and 2 healthy subjects (2026)
But overall, the dominant pattern seems to be daily administration
Adult in parenteral nutrition is not expected to cause major birth defects, miscarriage, or adverse maternal or fetal outcomes
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