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Minimal side effects: Offers a favorable safety profile with low risk of adverse reactions compared to other growth hormone secretagogues
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None of the three compounds have human safety data in pregnancy or breastfeeding, and they are not FDA-approved
A 2024 Medscape report described a patient who relapsed into disordered eating after ten years of recovery, experiencing rapid, dangerous weight loss and a full return of restricting behaviors after starting a GLP-1 medication, ultimately requiring hospitalization
Phase 2 trial results A phase 2, double-blind, randomised, placebo-controlled trial involving 338 adults with obesity or overweight revealed the potent weight-loss capabilities of retatrutide
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