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This redefinition of OA from a purely mechanical to a metabolic-inflammatory disorder opens transformative avenues for management, positioning nutritional intervention not merely as supportive care, but as a cornerstone of disease-modifying strategy
Treated APP/PS1 mice showed significant improvements in spatial learning and memory compared to untreated transgenic controls, with molecular analysis confirming activation of PI3K/AKT signaling in hippocampal tissue
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Kidney Disease: Improving Global Outcomes (KDIGO) Diabetes Work Group
Activity index = intensity of movement acceleration during a given time
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