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A starting dose of 1 mg or 1.5 mg, while not part of the standard branded protocol, allows the body to acclimate more gradually
These include anorectic effects driven by previously discussed central modulation of satiety and reward pathways and peripheral activation of vagal afferents, delayed gastric emptying, anti-inflammatory properties, potential impact on energy expenditure and the ability to reduce ghrelin levels, which are inherently elevated in PWS (30)
Oda et al
