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Diabetes 62 , 30443052 (2013)
Another study also carried out in HEK-293 cells showed that incretin heterodimers can form constitutively and that stimulation of GLP-1R with GLP-1 promotes incretin heterodimerisation whereas GIP stimulation reduces it ( q and -arrestin recruitment to the GLP-1R whereas GLP-1 stimulation enhances recruitment of G s to the GIPR
Sokos GG, Nikolaidis LA, Mankad S, Elahi D, Shannon RP: Glucagon-like peptide-1 infusion improves left ventricular ejection fraction and functional status in patients with chronic heart failure
Hashash JG, Thompson CC, Wang AY