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These improvements were dependent on the restoration of autophagy, confirmed by detection of increased levels of LC3 and components that enhance lysophagy (Reference Watchon, Wright and Ahel45, Reference Lumkwana, Peddie and Kriel75, Reference Freitag, Sterczyk and Wendlinger76)
The relationship between CSF1R signaling, monocyte-macrophage differentiation, and susceptibility to inflammatory bowel disease
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Global sensitivity analysis is then applied to examine the model behavior and identify the pathways with the greatest impact in control compared to RP conditions