Fig 2: Evolving Competitive Landscape in GLP-1 Based Obesity Medications Abbreviations: AHI: Apnea Hyperpnea Index, CKD: Chronic Kidney Disease, MONW: Metabolic Obesity Normal Weight, OOP: Out-of-pocket, OSA: Obstructive Sleep Apnea, WRC: Weight- related comorbidity
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Risks associated with oral semaglutide and GLP-1 pills include gastrointestinal symptoms, gallbladder issues, and rare cases of pancreatitis
Despite these advancements, critical gaps persist in understanding structure-activity relationships (SARs) and long-term biosafety profiles of co-delivery systems