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no significant differences were observed in the uptake of fluorescently labeled dextran, excluding the possibility that the observed differences are due to reduced DQ-BSA endocytosis (Supplementary Fig
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Results were consistent when evaluating triglycerides categorically or as a continuous variable. The current study was designed as a posthoc analysis of the trials to assess effects of semaglutide on MACE and its components across triglyceride levels
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The difference reflects tirzepatide's dual GLP-1 plus GIP receptor mechanism: the added GIP pathway enhances appetite suppression and fat metabolism beyond what GLP-1 alone provides
