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In pancreatic -cells, PC2 cleaves proglucagon to yield mature glucagon (29 aa), glicentin-related pancreatic polypeptide (GRPP) and the major proglucagon fragment (MPGF)
Development 112, 231240
[12] [14] For women aged 50 or over with new IBS-type symptoms, ovarian cancer should be considered and CA125 testing may be arranged
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