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Recent research suggests that reduced glutathione may be an even more effective antioxidant than vitamins C and E, and it is considered the master antioxidant. GSH protects tissues by neutralizing free radicals and improves the immune system by promoting antigen presentation and stimulating CD8 cells

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All of those require a known target

What they found: No serious adverse events triggered by AOD-9604 The most frequent side effects: headache (~5 %), occasional fatigue, at the same frequency as placebo No changes in IGF-1 levels, glycemia, blood pressure, heart rate No signals of cardiovascular, hepatic or renal toxicity Safety profile comparable to placebo Why it matters: From a safety perspective, AOD-9604 is one of the safest peptides in the clinical registry

24 Here we demonstrate that both of these obstacles are surmountable by using a 1 H-MRS editing method to measure CNS GSH levels, and a noninvasive (in)GSH administration strategy