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Brain Res Bull
In research models, elevated NNMT activity has been associated with: lower NAD levels, with downstream effects on mitochondrial energy production
it appears to attenuate excessive inflammatory signaling by influencing cytokine activity and cellular stress responses
The result: deep moisture that doesn't just sit on the surface, plus ingredients that actually signal collagen production
For functional medicine practitioners and researchers interested in this area, understanding what the evidence actually supports versus what remains speculative is the critical starting point
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