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GP may not know this as there was a recent change in BNF treatment guidance

no large-scale controlled human clinical trials establishing safety or efficacy currently exist

Additionally, hepatokines play a role in IR and lipid metabolism in conditions like obesity, type 2 diabetes mellitus (T2DM), and other metabolic disorders, suggesting their potential as novel regulators of energy metabolism [8, 9]

However, as of the time of this report, Cagrilintide is not approved by the U.S

Subcutaneous injection provides optimal bioavailability for systemic effects, while topical application targets localized skin concerns