Linus Pauling Institute Oregon State University Updated in July 2003 by: Jane Higdon, Ph.D
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The impact of oxidative stress is profound, causing damage to lipids, proteins, and DNA, which disrupts cellular function and contributes to disease progression
It should be noted that men with known conditions that would cause inflammation (such as genital tract infections, varicocele) or that used alcohol, smoked, or were currently taking antioxidants were all excluded from the study to create a more consistent base-line of existing oxidative stress (inflammation) between the groups This study also showed that the higher the measured levels of ROS, the more damage there was to sperm function
In case of both 10 and 20 mg Se 4+ /L culture medium, a similar increase in the OD (1.18 and 1.16) was observed after 24 h incubation