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It significantly upregulates VEGF (vascular endothelial growth factor) expression, stimulating endothelial cell proliferation and tubule formation

DOI: 10.1056/NEJMoa2502081 Davies MJ, Bajaj HS, Broholm C, Christiansen E, Fink LN, Hussein Z, et al

The most common signs and symptoms of Furosemide include the following extensions of the diuretic action: dehydration blood volume reduction hypotension electrolyte imbalance hypokalemia hypochloremic alkalosis The concentration of Furosemide that leads to toxicity or death is unknown

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