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Rapid Absorption and Clearance Plasma half-life of 26-38 minutes after subcutaneous injection substantially longer than native GHRH (which is degraded within seconds by DPP-IV) but still requiring daily dosing
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While efficacy endpoints for weight loss in those trials were modest, the compound exhibited a favorable safety profile, supporting its later GRAS designation for food use
Researchers may compare AOD-9604 with materials such as Cagrilintide, 5-Amino-1MQ, Triple Agonist, and MOTS-c when the study design supports that comparison
