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30-month stay, and the overall framework is less litigant-friendly to innovators than the U.S
Although direct in-patient persister identification is still technically challenging, in vivo and ex vivo biofilm models (rodent catheter and denture models, tissue explants) replicate biofilm architecture and have been used to show treatment failure and regrowth consistent with persister-mediated relapse (Li et al., 2015
No such changes in markers of oxidative stress, liver function, and glucose utilization were reported in the lifestyle intervention only group (101)
De Vadder, F
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