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However, cotadutide demonstrated superior performance in decreasing liver triglyceride levels and ameliorating mitochondrial functional markers in the liver compared to liraglutide, despite comparable reductions in body weight and food intake between the two treatments [43]

Starting body composition plays a major role, with individuals carrying higher body fat percentages often experiencing more dramatic absolute changes, while leaner individuals may see slower but steady improvements in stubborn fat areas

Ahmadi L, Eskandari N, Ghanadian M, Rahmati M, Kasiri N, Etamadifar M, Toghyani M, Alsahebfosoul F (2023) The immunomodulatory aspect of quercetin penta acetate on Th17 cells proliferation and gene expression in multiple sclerosis