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Research Summary IGF-1 LR3 is a recombinant long arginine analog of insulin-like growth factor 1 with a 13 amino acid N-terminal extension that reduces IGF-binding protein affinity, resulting in a ~120-hour half-life versus 15 hours for native IGF-1

Specifically, genes involved in gluconeogenesis, extracellular space and mitochondrial inner membrane pathways were upregulated in the AKK group (Fig

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