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The BMJ/MAGIC Group performed a systematic review to determine which patients may benefit from SGLT-2 inhibitors or GLP-1 receptor agonists

Hydration needs vary by individual, activity level, and medical conditions (those with heart failure or kidney disease may need specific guidance from their healthcare provider)

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Retatrutide is a triple-agonist peptide targeting GLP-1 + GIP + glucagon receptors simultaneously the most pronounced weight-loss data from any metabolic peptide studied to date