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Furthermore, we also found that the protective effect of GLP-1RAs against ED is partly mediated by reducing hypertension (mediated proportion: 3.22%, 95% CI: 1.21% to 5.23%) and CVD (mediated proportion: 3.06%, 95% CI: 0.51% to 5.62%) ( Figures 3 , 4 )
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First, extraction step was validated by analyzing a set of parallel blood samples extracted by different methods and analyzed with MS
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