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For weight management, continuation criteria are product-specific: liraglutide 3mg (Saxenda) should be discontinued if less than 5% weight loss is achieved after 12 weeks at the maintenance dose
Individuals harboring loss-of-function mutations in the APOC3 gene have significantly reduced levels of circulating triglycerides suggesting that targeting this protein may be an effective treatment of hypertriglyceridemias
71, 2014, Raoof N, Hoffmann J
References Raun K, et al
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