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B12 is safe on its own, but a few conditions call for extra care, which is why a provider reviews your history before treatment: Leber's hereditary optic neuropathy, a rare inherited eye condition, where certain forms of B12 may be a concern for the optic nerve

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However, as healthy habits can prevent a vitamin B12 deficiency, unhealthy ones can aggravate it, such as: Smoking: smoking damages the stomach cells and difficult vitamin B12 absorption, which for a bariatric surgery patient is already reduced

Most absorption problems aren't treatable but a few are - notably h pylori infection - which would mean that once that has been dealt with you would be able to absorb B12 from your diet so wouldn't need maintenance shots for life