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Current guidelines from the American Society for Metabolic and Bariatric Surgery (ASMBS) and International Federation for the Surgery of Obesity (IFSO) support consideration in patients with BMI 35 kg/m regardless of comorbidities, or BMI 30-34.9 kg/m with metabolic disease
The first oral GLP-1 pill received FDA approval on December 22, 2025 with introductory pricing of $149 per month for the lowest dose
Give it at least 68 weeks of consistent use
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For many companies, the safest path is to exit GLP-1 sales and refocus on compounds with lower regulatory and IP risk
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