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[2] Heffernan, M., Summers, R

Research indicates that patients with impaired kidney function, including premature neonates, who receive parenteral levels of aluminum at greater than 4 to 5 mcg/kg/day accumulate aluminum at levels associated with central nervous system and bone toxicity

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[54] In addition, elevated methylmalonic acid levels may also be related to metabolic disorders such as methylmalonic acidemia