Muoio DM, Noland RC, Kovalik JP, Seiler SE, Davies MN, DeBalsi KL, Ilkayeva OR, Stevens RD, Kheterpal I, Zhang J, Covington JD, Bajpeyi S, Ravussin E, Kraus W, Koves TR, Mynatt RL (2012) Muscle-specific deletion of Carnitine Acetyltransferase Compromises glucose tolerance and metabolic flexibility
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In summary, the cardinal pathological hallmarks of DCM include hyperglycemia, lipotoxicity, oxidative stress, inflammatory cascades, and fibrotic remodeling
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Nonetheless, the mechanism underlying the effects of GLP-1RAs in the cardiovascular system remain unclear