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31 In contrast to MEDI-573, BI836845 administration increased IGF-1 serum concentrations

Nonetheless, -KG competitors (DM-succinate and ITA) inhibit the YBX1AMPK axis in both cancer cells and 293T cells, suggesting that -KG availability may broadly determines energy sensing in human cells

The standard procedure of the kit (Sigma-Aldrich, MAK364) was followed to determine the total amount of reduced GSH in all samples

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