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Semaglutide's effect on gastric emptying represents the most clinically relevant consideration
A simple starting point: contract the pelvic muscles for 3-5 seconds, then relax for the same amount of time, repeating 10 times once or twice daily
Thigh (front of the upper leg): midway between hip and knee
Other reported or anticipated side effects based on Phase 2 data and the known pharmacology of the drug class include: Injection site reactions redness, bruising, or mild discomfort at the site of subcutaneous injection Fatigue commonly associated with caloric restriction and rapid weight loss Headache reported with GLP-1 receptor agonists as a class Increased heart rate (tachycardia) a known class effect of GLP-1 receptor agonists
2019;7:e617
