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Semaglutide and Cardiovascular Outcomes [PMID: 38381685] Laboratory literature summary: Semaglutide and Cardiovascular Outcomes
No severe hypoglycemia nor DKA were reported
However, a 2025 meta-analysis published in the Journal of the American Heart Association found that people who had been taking GLP-1 medications for 78 weeks or longer (roughly a year and a half) had a significantly higher risk of developing a DVT compared to non-users
References Mutsaers HAM, Merrild C, Norregaard R, Plana-Ripoll O
Previous studies have demonstrated that leptin dose-dependently inhibits glucose-stimulated insulin secretion in isolated pancreatic -cells, and significantly reduces insulin levels in perfused pancreatic preparations
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