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Here's how the researchers propose it works: You eat processed carbs (like white bread, fries, or candy) Your body releases lots of insulin, which tells your fat cells to grab and store calories from your blood A few hours later, your blood is low on fuel, and your brain and muscles are running on empty Your brain notices this and creates intense cravings for quick energy, which means more fast-acting carbs While compelling, the CIM cannot establish a causal relationship here and the researchers rightly note that it is difficult to accurately track daily calories outside a controlled environment

If the most uncomfortable period falls within the first four to eight hours after injection, and you inject at 8 PM or 9 PM, then the peak discomfort window aligns with your sleeping hours

Protein shakes work especially well when eating solid food seems hard

Take home message Both Mounjaro and Wegovy follow a similar pattern: slower weight loss at lower doses, a period of faster weight loss at higher doses, followed by slower weight loss as the body adapts to a lower set point

Torrego-Ellacura, M