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Then, Novo Nordisk worked on a new generation GLP-1 RA, semaglutide, and commercialized it successfully

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Serious but less common risks may include: Pancreatitis Gallbladder disease Severe dehydration Thyroid tumor warnings in animal studies Patients should always discuss personal medical history and risks with a qualified healthcare provider before starting treatment

One very small study found that people who used semaglutide had lower B12 levels, but these patients also had bariatric surgery prior to using semaglutideso its hard to say if using semaglutide would lead to a B12 deficiency, requiring additional B12