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A 2022 dose-response RCT (Yi et al., Geroscience) at 300/600/900 mg/day raised NAD+ dose-dependently with no safety issues at 60 days
doi: 10.1016/0024-3205(95)02302-x 153 MateenSRehmanMTShahzadSNaeemSSFaizyAFKhanAQet al
Surely wed think it crazy if it was suddenly decided that just 4 doses of vitamin C a year cured scurvy
Across a 2-4 week period, the vial gets punctured 20+ times
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