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Figure 3 elaborates how chemotherapy-sensitive cells undergo DNA damage (crosslinking, DSBs, base modifications) with impaired repair, leading to cell death, whereas resistant cells activate robust DNA repair mechanisms (NHEJ, BER, NER, MMR, HR), effectively repairing damage and promoting survival
Hori, M., Nobe, H., Horiguchi, K
Where GLP-1 primarily activates hypothalamic neurons involved in energy balance, amylin targets hindbrain circuits that regulate meal-specific satiety and food reward
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Glutathione for reducing liver diseases Liver cells are greatly damaged due to fatty liver disease, alcohol abuse, and hepatitis
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