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May impact the absorption of oral medications and requires caution before procedures requiring fasting due to delayed gastric emptying effect
Demographics disparities in sex and race/ethnicity associated with weight-loss response were mirrored across both tirzepatide and semaglutide, suggesting that the observed distribution is not specific to a single agent
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Average Weight Loss on Semaglutide In the main clinical trial that supported semaglutide's approval for weight management (the STEP 1 trial), adults who took the 2.4 mg weekly dose lost, on average, about 15% of their body weight over 68 weeks, compared with a much smaller amount in the placebo group
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