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By 8-12 weeks , the full benefits of treatment should become evident: substantial visceral fat reduction, better body composition, and enhanced cognitive function

HK2 HK2, which is essential for initiating glycolysis, is frequently overexpressed in various cancers

Cytochrome P450 is responsible for phase I metabolism (e.g., oxidation, reduction, hydrolysis, and hydration) (Hodek et al., 2002), and phase II metabolism involves various conjugation reactions, including glucuronidation, sulfation, and methylation (Zhu et al., 2024a)

Subsequently, lysates were centrifuged at 12,000 rpm for 15 min at 4 C to obtain clear supernatants