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The majority of patients were White (94%) and 46% were male
Lancet 402 , 504505 (2023)
There are mainly two approaches to target the incretin system (1) via inhibiting the enzymatic action of DPP4 and thereby upregulating GLP-1 levels physiologically and (2) via increasing GLP-1 levels pharmacologically
The nucleus accumbens, a key brain reward center, contains abundant GLP-1 receptors
So, when you take a glutathione supplement orally or by injection , it will hang around in the extracellular environment but will not be able to enter cells intact to combat oxidative stress
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