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In vitro and animal models indicate that GLP-1RAs, such as liraglutide, mitigates cartilage degradation and downregulates inflammatory mediators like IL-6, prostaglandin (PG)E2, and nitric oxide [128]

Provider assessment of baseline insulin production, residual beta-cell function, and cardiovascular risk guides the decision to initiate dual therapy

These disturbances could result from blood sugar fluctuations, blood pressure changes, or other systemic effects of Wegovy

You dont need to face these changes on your own

Seek urgent medical care if you experience blood glucose levels persistently above 300 mg/dL, symptoms of severe hyperglycemia, dehydration, or signs of diabetic ketoacidosis