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8 People living with MASH often experience few or no specific symptoms in the early stages of the disease, which often results in a delayed diagnosis
Both are legitimate, mechanistically coherent, and encouraging as far as they go
SIDE EFFECTS DSIP is generally well-tolerated in research protocols due to its function as a natural neuro-modulator rather than a systemic sedative
Pros of GLP-1s: Non-surgical option Can lead to 1520% body weight loss in clinical trials May improve blood sugar, cholesterol, and inflammation Weekly injections, often self-administered Cons of GLP-1s: Real-world weight loss may be lower than clinical trials (510%) Side effects include nausea, vomiting, fatigue, and gastroparesis High cost and limited insurance coverage Weight may return if medication is stopped What is weight loss surgery
doi:10.3389/fneur.2014.00206
