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These features support the rationale for using glucagon in combination with other gut hormones as described below

10.1016/j.biopha.2021.112448 41 DucaF

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Consequently, ECL1 adopted a more relaxed conformation, making peptide 20 straighter by shifting its tip toward the transmembrane domain (TMD) core by 4.2 (measured by the C of L27 P )

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