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Novo is banking on the pills first-to-market advantage to revitalize sales in the U.S., where it has lost ground to Lilly

Melatonin can sometimes cause grogginess, vivid dreams, or a hangover feeling the next morning if the dose is too high

Metformin is another popular and effective option, and according to the American Diabetes Association, DPP-4 inhibitors, SGLT2 inhibitors, sulfonylureas, and thiazolidinediones are other viable alternatives

FDA Telehealth Warning Letters In early March 2026, the FDA reportedly issued warning letters to multiple telehealth companies regarding compounded GLP-1 marketing practices, with concerns including misleading marketing claims, implications of equivalence with FDA-approved drugs, and obscuring product sourcing