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As it relate to compounding pharmacies, the historical legacy of Apothecaries, which has evolved in compounding pharmacies, is at a flash point vis a vis therapeutic peptides
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For example,a cohort study of depressive patients and healthy controls found that MTHFR polymorphism were more common in the individuals with depression history compared to controls 67 , while a study over a 60-month follow-up with depressed subjects indicated that the CC genotype of MTHFR C677T were more likely to have more severe symptoms compared to TT genotype carriers 68
Community observations should inform but not replace careful individual risk assessment
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