Thrombocythemia and pulmonary embolism were reported in 0.1% to 1% of patients during clinical trials of topiramate as monotherapy or adjunct therapy for epilepsy
She continues, "The cardiovascular protection and other emerging benefits, such as improvements in outcomes related to metabolic-associated liver disease and obstructive sleep apnea, are additional benefits of these medications." About the Author Jennifer Fisher, MMSc, PA-C, Health Writer About the Reviewer Chika V
2025 set the tone with high-profile battles like the Metsera bidding war between Pfizer and Novo Nordisk which finally closed, with Pfizer winning, for $10bn [17] , underscoring the strategic value of next-generation assets such as Metseras long-acting injectable asset, MET-097i
In muscle, Akt phosphorylation leads to mTOR activation and suppression of atrophy genes
It works through a different mechanism than antibiotics, which target bacterial infections, meaning the two medication classes do not typically interfere with each other's effectiveness