Leslie WS, Ford I, Sattar N, Hollingsworth KG, Adamson A, Sniehotta FF, et al
106 This derepresses Np63 expression, promoting lineage plasticity and the emergence of double-negative prostate cancer (DNPC) under androgen deprivation therapy
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Protein band intensity was quantified using the ImageJ program (rsbweb.nih.gov/ij/download.html) and normalized with -actin (for total homogenate) or lamin-A (for nuclear extracts)
Exogenously, they arise from exposure to environmental factors like ultraviolet (UV) radiation, pollution, tobacco smoke, and industrial chemicals [3]