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Creatine plays an essential role in energy production and is shown to improve athletic performance
This enhances the expression and activity of NRF2, resulting in significantly reduced ROS levels in lipopolysaccharide (LPS)-activated microglial cells [147]
Additional warnings include risk of pancreatitis, gallbladder disease, acute kidney injury, hypersensitivity reactions, and caution in patients with severe gastrointestinal disease including gastroparesis
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PMID: 14584018 National Institute of Mental Health [Internet] Bethesda, MD
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