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Dosing Methyl B12 B12 is a water soluble vitamin, meaning the body uses what it needs and then excretes excess in the urine
Receptor Supersensitivity Blockade In the landmark 1997 Sikiric study published in Biological Psychiatry (PMID: 9547930), mice pretreated with haloperidol (a dopamine antagonist) developed behavioral supersensitivity to amphetamine challenge
If you miss a dose, most protocols suggest taking it as soon as you remember, provided the next scheduled dose is at least 3 days (72 hours) away
Peptide Reconstitution Calculator: Practical Examples A peptide reconstitution calculator answers a different question than a dosage calculator
As vitamin B12 is water soluble any excess is excreted through the urine and it can safely be given every 3 months
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