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These include the treatment of nonalcoholic steatohepatitis (NASH) in T2D patients due to the peptides effects on lipid metabolism, inflammatory response, and body composition [10, 11]
Pregnancy and breastfeeding contraindications apply strictly to Botox with no human safety data justifying absolute avoidance during these periods, while topical peptides show minimal systemic absorption creating theoretical safety though conservative approach suggests avoiding copper peptides during pregnancy due to copper exposure concerns
However, patients must have an empty stomach prior to surgery due to increased risks of aspiration and subsequent morbidity and mortality (Klein, et al., 2023)
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