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Tirzepatide targets two pathways (GLP-1 and GIP), while semaglutide targets GLP-1 alone
The method can assay GSH in whole blood, plasma, serum, lung lavage fluid, cerebrospinal fluid, urine, tissues and cell extracts and can be extended for drug discovery/pharmacology and toxicology protocols to study the effects of drugs and toxic compounds on glutathione metabolism
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CXCL10-mediates macrophage, but not other innate immune cells-associated inflammation in murine nonalcoholic steatohepatitis
Rudrapal et al., 2024), antidiabetic/antiobesity (Gowd et al., 2019), anticancer (Westfall et al., 2021), and antimicrobia (Rudrapal et al., 2022c) activities of these polyphenols by producing polyphenol metabolites which protect gut barrier integrity, mitigate cellular oxidative stress and serve protective functions against inflammations/immune reactions and associated cellular damages
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