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(A) GLP-1 can induce fibronectin type III domain-containing protein 5 (FNDC5) expression in pancreatic -cells through the interaction of its downstream transcription factor cAMP-response element binding protein (CREB) with binding elements in the FNDC5 promoter, thereby promoting the conversion of white adipose tissue (WAT) to brown adipose tissue (BAT)
Retrieved from Hausner, H., Derving Karsbl, J., Holst, A
Animals in the second group were treated with one intraperitoneal injection of polychlorinated biphenyl (Aroclor 1254) 500 mg kg -1 and were sacrificed after 7 days, while those in the third group were treated with intraperitoneal injection of 3-methylcholanthrene 20 mg -1 kg -1 day -1 for two days and were sacrificed 48 hours after treatment
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