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However, understanding VLDL requires context from other metabolic markers including triglycerides (which directly determine calculated VLDL), HDL and LDL cholesterol, insulin and glucose for assessing insulin resistance, liver enzymes (ALT, AST) to evaluate fatty liver, and inflammatory markers like hs-CRP
& Reagan, L
Incretin hormones: Their role in health and disease
These findings shed light on mechanisms underlying 5FU resistance and propose a rational strategy for combination therapy in CRC, emphasizing the potential clinical benefit of targeting mitochondrial metabolism to overcome resistance and enhance patient outcomes
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